NEWS

NeoPL® human platelet lysate is a xeno-free, growth-factor-rich replacement for FBS, made from pathogen-tested donor platelets collected at FDA-licensed US blood centers.

5% vs 20%NeoPL® at 5% outgrew 20% FBS
>99.3%MSC marker expression maintained
+55%more live cells with NeoPL®-Boost vs another hPL

Faster growth at a quarter of the concentration

051015202530051015202530DaysCumulative PDs5% NeoPL®-Nova20% FBS10% FBS
UC-MSCs in α-MEM: ~26 cumulative PDs with 5% NeoPL®-Nova vs ~23 (20% FBS) and ~14 (10% FBS) at ~day 29.

MSC identity preserved

SupplementCD105CD90CD73CD44CD29CD13
NeoPL®-Apex99.37%99.97%99.80%99.86%99.97%99.88%
NeoPL®-Nova99.82%99.97%99.89%99.82%99.99%99.97%
Flow cytometry; typical spindle morphology retained in UC-, AD- and BM-MSCs.

NeoPL®-Boost vs a standard hPL

120 h culture, 0.2 × 10⁶ cells seeded5% NeoPL®-Boost5% other hPL
Live cells (×10⁶)1.160.75
Doubling time (h)47.162.6
Viability96%92.5%
Cumulative PDL5.833.77
Formats: NeoPL®-Boost, -Nova (heparin-free, fibrinogen-depleted) and -Apex (fibrinogen-depleted), in research and GMP grade, 100 mL and 500 mL.
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AICON-BIO internal data. Results may vary with cell source and culture conditions.