Antibody recognizes 2019-nCoV Nucleocapsid Protein
Cultrued in vitro under conditions free from animal derived components.
[Product buffer solution]
PBS, pH 7.4, 0.09 % sodium azide (NaN3)
[Shelf life and storage]
24 months from manufacturing at <-20 °C; 1 month, 2 to 8 °C under sterile conditions.
Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. N protein packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.
PARAMETERS TESTED ON EACH LOT
[Product appearance] Liquid, may turn slightly opaque during storage
[Product concentration] 5.0 mg/ml (+/- 10 %)
[Immunoreactivity] 80–120 % compared to the reference sample in an ELISA test.
[Purity] ≥ 95 %
TEMPERATURE, TIME RESULT
+37 °C, 7 days OK
Please note that pair recommendations are based on results obtained by our laboratory. Equally good results may be obtained using other pairs and therefore these recommendations are only indicative.
FOR RESEARCH OR FURTHER MANUFACTURING USE ONLY