3 in 1 Cardiac combo Test
specimen: serum, plasma
In vitro use only
Detect cardiac marker
Troponin I test:
Cardiac Troponin (cTnl) is a protein found in cardiac muscle with a molecular weight of 22.5 kDa.Troponin I
is part of a three subunit complex comprising of Troponin T and Troponin C. Along with tropomyosin, this structural complex
forms the main component that regulates the calcium sensitive ATPase activity of actomyosin in striated skeletal
andcardiac muscle. After cardiac injury occurs, Troponin I is released into the blood 4-6 hours after the onset of pain.
The release pattern of cardiac Tnl is similar to CK-MB, but while CK-MB levels return to normal after 72 hours,
Troponin I remains elevates for 6-10 days, thus providing for a longer window of detection for cardiac injury. The
high specificity of cTnl measurements for the identification of myocardial damage has been demonstrated in
conditions such as the perioperative period, after marathon runs, and blunt chest trauma. cTnl release has also
been documented in cardiac conditions other than acute myocardial infarction /AMI) such as unstable angina
congestive heart failure, and ischemic damage due to coronary artery bypass surgery.Because of its high
specificity and sensitivity in the myocardial tissue, Troponin I has recently become the most preferred biomarker
for myocardial infarction.Troponin I (cTnl) Test is a simple test that utilizes a combination of colloidal gold conjugate,
biotinylated anti-cTnl antibodies and streptavidin to selectively detect cTnl in whole blood, serum or plasma.
The minimum detection level is 0.5 ng/mL.