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ACE-2 (Mammalian, C-Avi-6His)-100ug

ACE-2 (Mammalian, C-Avi-6His)-100ug

  • Model: NCY51
  • Price:

    $1,000.00

    Qty:
    Note: Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.

    Product Description

    [Packing] 100ug

    [DESCRIPTION]

    Biotinylated Recombinant Human Angiotensin-Converting Enzyme 2 is produced by our Mammalian
    expression system and the target gene encoding Gln18-Ser740 is expressed with a Avi, 6His tag at the C-
    terminus.

    Accession:Q9BYF1

    Known as:Angiotensin-Converting Enzyme 2; ACE-Related Carboxypeptidase; Angiotensin-
    Converting Enzyme Homolog; ACEH; Metalloprotease MPROT15; ACE2

    [QUALITY CONTROL]

    Mol Mass:86.2kDa       AP Mol Mass:110-140kDa, reducing conditions.

    Purity:Greater than 95% as determined by reducing SDS-PAGE.

    Endotoxin:Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.

    Biotin:Protein Ratio    The biotin to protein ratio is 0.5-1 as determined by the HABA assay.

    [FORMULATION]

    Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 300mM NaCl, 1mM ZnCl 2 , 10% Glycerol, pH 7.4.

    [SHIPPING]

    The product is shipped on dry ice/polar packs.
    Upon receipt, store it immediately at the temperature listed below.

    [STORAGE]

    Store at < -20°C, stable for 6 months after receipt.
    Please minimize freeze-thaw cycles.

    [BACKGROUND]

    Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease
    of the ACE family, the ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II
    as a carboxypeptidase, ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin
    1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be high
    expressed in testis, kidney and heart, in colon, small intestine and ovary at moderate levels. Captopril
    and lisinopril as the classical ACE inhibitor don’t inhibit ACE-2 activity. ACE-2 may play an important role
    in regulating the heart function.

    [SDS-PAGE]

     

    FOR RESEARCH OR FURTHER MANUFACTURING USE ONLY
    Aicon Biotech,Inc

    Features

    • Model: NCY51
    • 999 Units in Stock

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    Shipping info

    $50.00 to United States

    Contact us to order

    +1(206)6369998 +1(503)2681752


    This product was added to our catalog on Tuesday 10 March, 2020.